Clinical trials

Clinical trials at West Jefferson Medical Center

At WJMC, our mission is to provide patients with access to the latest advancements in medical research and innovative healthcare. Through our robust and growing clinical trials program, we are helping to shape the future of medicine—right here in our community. These research studies give patients the opportunity to explore promising new treatments and therapies that are not yet available to the general public.

Whether you're facing a complex diagnosis, seeking alternatives to standard care, or simply want to contribute to scientific discovery, clinical trials can offer additional paths forward. By participating, you not only gain access to leading-edge care but also play an essential role in helping researchers and physicians better understand diseases, improve treatment outcomes, and develop the next generation of medical breakthroughs.

West Jefferson Cancer Clinical trials offerings

Learn more about how we are advancing medicine and enhancing lives through clinical trials.

Breast

• Randomized Non-Inferiority Trial Comparing Overall Survival of Patients Monitored with Serum Tumor Marker Directed Disease Monitoring (STMDDM) versus Usual Care in Patients with Metastatic Hormone Receptor Positive HER-2 Negative Breast Cancer
• Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III Study
• LoTam: A Randomized, Phase III Clinical Trial of Low-Dose Tamoxifen for Selected Patients with Molecular Low-Risk Early-Stage Breast Cancer

Gastrointestinal

• Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

Cervical

• Induction Pembrolizumab and Chemotherapy followed by Pembrolizumab before chemoradiation and pembrolizumab maintenance compared to standard chemoradiation with pembrolizumab followed by pembrolizumab maintenance in high-risk cervical cancer.

Endometrial and Uterine

• A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined with Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma
• A Phase III Trial Of The Impact Of Sentinel Lymph Node Mapping On Patient Reported Lower Extremity Limb Dysfunction In Endometrial Cancer
• A Randomized Phase III Trial of Carboplatin, Paclitaxel, Pembrolizumab Versus Carboplatin, Paclitaxel, Bevacizumab Versus Carboplatin, Paclitaxel, Pembrolizumab, Bevacizumab in the Treatment of pMMR, TP53 Mutated Advanced or Recurrent Endometrial Cancer

Ovarian cancer

• A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or Without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy

Miscellaneous

• Blinded Reference Set For Multicancer Early Detection Blood Tests
• A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]
• Establishment of a national biorepository to advance studies of immune-related adverse events
• Multicenter Randomized Controlled Trial Comparing Brief Behavioral Therapy for Cancer Related Insomnia (BBT-CI) and Healthy Eating Education Learning (HEAL)