Clinical trials

Clinical trials at West Jefferson Medical Center

At WJMC, our mission is to provide patients with access to the latest advancements in medical research and innovative healthcare. Through our robust and growing clinical trials program, we are helping to shape the future of medicine—right here in our community. These research studies give patients the opportunity to explore promising new treatments and therapies that are not yet available to the general public.

Whether you're facing a complex diagnosis, seeking alternatives to standard care, or simply want to contribute to scientific discovery, clinical trials can offer additional paths forward. By participating, you not only gain access to leading-edge care but also play an essential role in helping researchers and physicians better understand diseases, improve treatment outcomes, and develop the next generation of medical breakthroughs.

West Jefferson Cancer Clinical trials offerings

Learn more about how we are advancing medicine and enhancing lives through clinical trials.

Breast

• Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III Study

Brain/CMS

• Phase III Trial of Radiotherapy Followed by Adjuvant Temozolomide in Combination with the IDH Inhibitor Vorasedinib versus Placebo in IDH-Mutated Newly-Diagnosed Grade 3 Astrocytomas
• A Randomized Phase III Study Comparing Temporally Modulated Pulsed Radiation Therapy (TMPRT) versus Standard Radiation Therapy with Temozolomide for Adults with Newly Diagnosed MGMT-Unmethylated Glioblastoma

Cervical

• Induction Pembrolizumab and Chemotherapy followed by Pembrolizumab before chemoradiation and pembrolizumab maintenance compared to standard chemoradiation with pembrolizumab followed by pembrolizumab maintenance in high-risk cervical cancer.

Colon and Rectal

• Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

Endometrial and Uterine

• A Phase III Trial Of The Impact Of Sentinel Lymph Node Mapping On Patient Reported Lower Extremity Limb Dysfunction In Endometrial Cancer
• A Randomized Phase III Trial of Carboplatin, Paclitaxel, Pembrolizumab Versus Carboplatin, Paclitaxel, Bevacizumab Versus Carboplatin, Paclitaxel, Pembrolizumab, Bevacizumab in the Treatment of pMMR, TP53 Mutated Advanced or Recurrent Endometrial Cancer
• A Phase II Study of Tailored Adjuvant Therapy in Pole-Mutated and p53-Wildtype/NSMP Early-Stage Endometrial Cancer (RAINBO BLUE & TAPER)

Ovarian cancer

• A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or Without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy

Pancreatic cancer

• A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)

Miscellaneous

• Blinded Reference Set For Multicancer Early Detection Blood Tests
• A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]
• Establishment of a national biorepository to advance studies of immune-related adverse events